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The Ordering Process — Simple
These days we can do so many things from the comfort of our home, so why not a DNA test as well? Absolute DNA Services has streamlined the process for the Inherited Cancer Panel, so it’s as easy as:
- Choose your test and order it online.
- Pay for your test.
- We require that you consult a genetic counsellor both prior to, and after, your test. Absolute DNA Services will request a referral form to be filled out by your GP, genetic counsellor, or specialist. A genetic counsellor can assist in deciphering your results so that you get the best and most accurate information relating to your individual test.
- When you order the Inherited Cancer Panel, Absolute DNA Services will send you the appropriate referral forms for your genetic counsellor or doctor to complete. We then send your sample collection kit directly to one of our affiliated pathology centres. We will arrange your appointment for sample collection.
- After analysis, your results will be sent to your genetic counsellor or doctor, at which time they will discuss them thoroughly with you.
About Cancer Panel Testing
Cancer affects us all. We all know someone who has it, survived it, or sadly, was taken too soon by it. Although some cancers develop due to a combination of chance and our environment, up to 10% of all cancers are linked to a relative or an inherited gene mutation.
A cancer that is caused by a genetic mutation is called a hereditary cancer, and is most commonly passed on from parents to their children. Hereditary cancers often develop earlier than other forms of cancer, and can sometimes be more aggressive than the same type of cancer in a non-hereditary patient.
Our unique DNA are made up of small molecules, called nucleotides, which carry instructions for how the different proteins in our body should be put together. If there is a difference in the sequence of nucleotides, this can result in changes to the way proteins function. This is called a mutation, and results in the creation of a new genetic trait, or occasionally, a disorder or a disease.
Panels
IP, AKT1, ALK, ANTXR1, APC, ASCC1, ATM, ATR, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, BUB1, BUB1B, CACNA1D, CBL, CDC73, CDH1, CDK4, CDKN1B, CDKN2A, CHEK2, CTHRC1, CYLD, DDB2, DICER, EGFR, ELAC2, EPCAM, ERCC2, ERCC3, ERCC4, ERCC5, EXT1, EXT2, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FH, FLCN, GPC3, HNF1A, HNF1B, HOXB13, KDR, KIT, KLLN, LIG4, MAX, MEN1, MET, MITF, MLH1, MLH3, MRE11A, MSH2, MSH6, MSR1, MTAP, MUTYH, MYH8, NBN, NCOA4, NF1, NF2, NTRK1, PALB2, PALLD, PDGFRB, PHOX2B, PIK3CA, PMS2, POLD1, POLE, POLH, PPM1D, PRF1, PRKAR1A, PRSS1, PTCH1, PTCH2, PTEN, PTPN11, RAD50, RAD51C, RAD51D, RB1, RECQL4, RET, RHBDF2, RNASEL, RNF168, RSPO1, RUNX1, SBDS, SDHA, SDHAF2, SDHB, SDHC, SDHD, SETBP1, SH2D1A, SLX4, SMAD4, SMARCB1, SMARCE1, SPINK1, SPRED1, STK11, SUFU, TERT, TGFBR1, TMEM127, TP53, TSC1, TSC2, VHL, WAS, WRN, WT1, XPA, XPC, XRCC2.
Sample Collection
This is a simple test that only requires a blood draw, from which your DNA is extracted and analysed using Next Generation Sequencing technology. The blood draw must be performed by a qualified sample collector and will incur an additional cost. It is important to note that this test also requires you to attend a genetic counselling session with a qualified professional, who will also receive your results, to then discuss at a time that suits you both.
The Ordering Process — Simple
These days we can do so many things from the comfort of our home, so why not a DNA test as well? Absolute DNA Services has streamlined the process for the Extended Carrier Screening, so it’s as easy as:
- Choose your test and order it online.
- Pay for your test and any extras you require.
- You will get your home sample collection kit in the mail. The kit will contain everything you need to undertake the test from the comfort of your home.
- Receive your results within a quick timeframe.
About Carrier Testing
Our Extended Carrier Screening offers a comprehensive screening option, covering 420 genes, including genes associated with Cystic Fibrosis, Spinal Muscular Atrophy and Fragile X.
The genes covered by this panel are associated with more than 700 unique commonly inherited diseases including the most common forms of inherited deafness, blindness, heart disease, immunodeficiency, and various ataxias, anaemias, and treatable metabolic syndromes.
If your gene of interest is not covered on one of our carrier screening panels, or if you have a blood relative who is a carrier of, or affected by, an inherited disorder, a targeted panel may be more appropriate to detect the specific gene or mutation. Please contact us and our team will assist you with finding a gene panel that suits your specific needs.
What is a genetic carrier?
Most people carry faulty genes that can potentially cause health problems for your child. Genes are instructions that tell our bodies how to develop and work. You have 2 copies of each gene.
If you have one working copy of a gene and one faulty copy of a gene, you are known as a carrier. This means that:
- You won’t have the health problem yourself
- You can pass on your copy of the faulty gene to any children you have
If you and your partner are both carriers for the same condition:
Every child you conceive will have a 1 in 4 chance of being born with the condition
Every child you have will have a 1 in 2 chance of being a carrier (possessing one faulty gene)
The Ordering Process — Simple
Absolute DNA Services has streamlined the process for the Pharmacogenomics Panel, so it’s as easy as:
- Choose your test and order it online.
- Pay for your test.
- We require that you consult a genetic counsellor both prior to, and after, your test. Absolute DNA Services will request a referral form to be filled out by your GP, genetic counsellor, or specialist. A genetic counsellor can assist in deciphering your results so that you get the best and most accurate information relating to your individual test.
- When you order the Pharmacogenomics PGx Test, Absolute DNA Services will send you the appropriate referral forms for your genetic counsellor or doctor to complete. We then send your sample collection kit directly to one of our affiliated pathology centres. We will arrange your appointment for sample collection.
- After analysis, your results will be sent to your genetic counsellor or doctor, at which time they will discuss them thoroughly with you. You will receive your result within 2-3 weeks.
About Pharmacogenomics Panel
As everyone has a unique genetic makeup, this can affect how you will respond or react to certain medications. A medication or dose that works for one person may be ineffective or cause harmful side effects for another. Through pharmacogenomics testing, individualised medicine treatment plans can be developed based on each patient’s genetic makeup to determine optimal drugs and dosages, and limit harmful side effects. The way in which medications are metabolised is largely dependent on your unique genetic makeup. Some medications are used by the body quickly, while others are slower to react. This can change how successful a medication is for you and your needs.
Who should have PGx testing done?
PGx testing is available to everyone but may be most useful for patients who are currently on, or about to begin taking, medications for any of the conditions covered. It may also be useful for people who have tried numerous drugs to find one that may effectively treat their symptoms.
PGx is particularly relevant in psychiatry where antidepressants are essential components in treatment. Around 30-50% of patients do not respond to their first antidepressant and lengthy trials are often required before the optimal treatment type and dose is identified. Patients who have had genetically guided prescribing may have a greater chance of remission compared to patients without genetic prescribing.
Our PGx panel also covers over 60 common oncology drugs. For cancer patients who are about to commence treatment, this may help identify which drugs are likely to be effective. For cancer patients who are currently on treatment, PGx testing may identify new treatment options or identify if and why current medications aren’t effective.
Advantages
- Decreasing and potentially eliminating the need for a “trial and error” approach to find effective therapy and dosages.
- Decreasing the number of adverse drugs reactions a patient may experience.
- Saving patients time and money on ineffective medications.
- Decreasing the amount of time patients are on medications.
Panels
Our Pharmacogenomics Panel uses next generation sequencing to analyse genes related to 40 known drug-metabolizing enzymes (DMEs) – ABCB1, ABCG2, ADRA2A, ANKK1, APOE, COMT, CYP1A2, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP3A4, CYP3A5, DBH, DPYD, DRD1, DRD4, F2, F5, GABRA6, GABRP, GRIK4, HLA-A*3101, HLAB*1502, HLA-B*5701, HTR2A, HTR2C, ITGB3, KIF6, MTHFR, OPRD1, OPRK1, OPRM1, SLCO1B1, TPMT, UGT1A1, UGT2B15, UGT2B7 and VKORC1.
There are 12 PGx panels available, and the initial cost is for 2 tests. Additional tests can be purchased by arrangement.
Click below to explore what medication each unique panel targets!
Anaesthesiology
- Anaesthesiology
- Endocrinology
- Infectology
- Internal Medicine
- Modulation of Cardiovascular Function
- Neurology
- Oncology, Haematology
- Organ Transplantation
- Pain Management
- Psychiatry
- Recreational Drugs
- Urology
Discover your ability to metabolise the following medications:
- Anaesthetic
- Muscle Relaxants
The Ordering Process — Simple
These days we can do so many things from the comfort of our home, so why not a DNA test as well? Absolute DNA Services has streamlined the process for the Inherited Diseases Panel, so it’s as easy as:
- Choose your test and order it online.
- Pay for your test and any extras you require.
- You will get your home sample collection kit in the mail. The kit will contain everything you need to undertake the test from the comfort of your home.
- Receive your results within a quick timeframe.
About Inherited Disease Testing
Inherited diseases, also known as genetic disorders, are caused by one or more abnormalities in the human genome, and occur when an altered gene is passed from a parent to a child.
There are two main ways in which genetic diseases are referred to. They are dominant inheritance and recessive inheritance.
- When a disorder is dominant, there is a 50% chance that the gene will be passed on to the child from the parent.
- When a disorder is recessive, the gene will only manifest if 2 copies of the gene are inherited, one from each parent. A child with a recessive gene has a 25% chance of inheriting both copies of the defective gene and a 50% chance of inheriting just one copy of the defective gene from either parent.
The Ordering Process — Simple
Absolute DNA Services has streamlined the process for ordering a Single Genotype DNA Profile, so it’s as easy as:
- Choose your test and order it online.
- Pay for your test.
- You will get your home sample collection kit in the mail. This kit contains everything required to undertake the test at home. This can include instructions for use, oral swabs, consent forms, and a return envelope.
- Receive your results in a quick timeframe (within 5-7 working days of receiving samples).
About DNA Profiles
Your Single Genotype DNA Profile can be used in legal matters involving inheritance, where you may have to verify a biological relationship, only if you select the legal option at checkout.
It can also be used by those with high risk occupations, or those with a high public profile who may need to ensure their identity in the event of a ransom demand resulting from a kidnapping. It can also be of use if you go missing and need to be identified.
About Surrogacy Testing
Some couples who are unable to have a baby in the traditional way, opt to use a surrogate.
A surrogate is a woman acts on behalf of a couple, carrying the baby during pregnancy, then returning the baby to the parents once it is born.
There are various types of surrogacy.
Gestational Surrogacy
Involves implanting an embryo (created using sperm and egg from the intended parents) into the uterus of the surrogate using in-vitro fertilisation (IVF). This means that the intended parents are both biologically related to the unborn baby.
Traditional Surrogacy
Uses the egg of the surrogate and the sperm of the father. This means that the surrogate is the biological mother of the child. At birth, the surrogate legally gives up all rights to the child, and the intended mother will be required to adopt the child.
Surrogacy is legal in Australia, but for a number of reasons, many couples opt to seek a surrogate from overseas. This means that the child is born overseas and automatically becomes a citizen of that country.
Absolute DNA Services can assist, with our Surrogacy DNA Test. The results of this test can help to confirm the relationship between the baby and parents, and will be admissible in court according to Australian legislative requirements.
How does it work?
The Department of Immigration and Citizenship requires that the surrogate child must have a passport and visa. After processing, the department issues a case number and organises a DNA sample collection, usually in the child’s country of birth. The sample is usually taken in the Embassy or High Commission by a nominated doctor.
All DNA will be tested once samples from the surrogate child and alleged parents are received.
Surrogacy By State
Each state and territory in Australia has different laws on surrogacy. It is advised that you check the Surrogacy Australia website for more information.
The Ordering Process — Simple
Absolute DNA Services has streamlined the process for the Prenatal Genetic Screening, so it’s as easy as:
- Choose your test and order it online.
- Pay for your test and any extras you require.
- When Absolute DNA Services receives your order, we will send you a list of our recommended Pathology Collection Centres. The sample collection kit will include everything you need, including mouth swabs, vials for blood collection, and full instructions.
- Receive your results within a quick timeframe.
About Absolute’s Prenatal Screening
For all of the excitement and anticipation that comes with a pregnancy, there is an equal amount of trepidation. Will labour hurt? Will I be a good parent? What if there’s something wrong with my baby? For some people, the chance that their child may have a genetic condition causes much concern.
Absolute DNA Services alleviates this worry, with the non-invasive pregnancy peace of mind test. Using a standard medical blood sample, this test is 100% safe, and does not involve the removal of amniotic fluid from the uterus, as performed during an amniocentesis.
It is important to note that this test is not a diagnostic test, and cannot replace an amniocentesis or a chorionic villus sampling. A diagnostic test may be advised if you receive a positive result from the screening test.
Screening for 18 genetic conditions, including Down Syndrome, the test can be taken from as early as 10 weeks post- conception.
How does it work?
After conception, the baby’s DNA enters the mother’s bloodstream. Once our scientists have obtained a sample of the mother’s blood, they separate the maternal plasma from the rest of the blood.
In this plasma, maternal DNA and cell-free foetal DNA is analysed and the ratio of foetal chromosomes is proven. Results that confirm Down Syndrome will indicate a higher ratio of genetic material in relation to chromosome 21.
Genetic Conditions Detected
Trisomies
- Down Syndrome
- Edward’s Syndrome
- Patau Syndrome
- Trisomy 9
- Trisomy 16
- Trisomy 22
Sex Chromosome Abnormalities
- Jacob Syndrome
- Klinefelter’s Syndrome
- Triple X
- Turner’s Syndrome
Deletion Syndromes / Microdeletion Syndromes
- Angelman Syndrome
- Cri-u-chat Syndrome
- DiGeorge Syndrome 2
- Jacobson Syndrome (11q23)
- Prader-Willi Syndrome
- Van der Woude Syndrome
- 1p36 deletion
- 16p12.2-p11.2 deletion
- 2q33.1 deletion
The Ordering Process — Simple
Absolute DNA Services has streamlined the process for the 3-in-1 Prenatal Bundle, so it’s as easy as:
- Choose your test and order it online.
- Pay for your test and any extras you require.
- When Absolute DNA Services receives your order, we will send you a list of our recommended Pathology Collection Centres. The sample collection kit will be sent directly to your nominated centre.
- Receive your results in a quick timeframe.
About Absolute’s Prenatal Package
The 3-in-1 Prenatal Bundle offers the ultimate in comprehensive testing regarding your baby. The package provide 3 tests for one set price:
- Gender Test – Find out if your growing bump is a boy or a girl, from as early as eight weeks following conception. Results have a 98% accuracy rate and are as simple as a standard blood draw from your medical practitioner.
- Non-invasive Prenatal Screening – This test provides peace of mind for expectant parents, screening for Down Syndrome and 17 additional chromosomal abnormalities. Using a simple blood sample, this test is 100% safe and non-invasive.
- Non-invasive Prenatal Paternity Test – Zero risk and 99.9% accuracy. You provide a sample of maternal blood and a DNA sample from the alleged father; this can be in the form of a blood sample, mouth swab, or fingernail swab.
The Ordering Process — Simple
Absolute DNA Services has streamlined the process for the Baby Gender Test, so it’s as easy as:
- Choose your test and order it online.
- Pay for your test and any extras you require.
- You will get your sample collection kit in the mail. The kit will contain everything required, including the vials you will need to take to your medial practitioner for your blood draw.
- Receive your results within a quick timeframe.
About Gender Testing
For those who want to know the gender of baby sooner rather than later, the Gender DNA Test offers 98% accuracy, and can be undertaken as early as eight weeks post-conception.
All that is required is a blood sample, taken at a standard blood draw by a doctor or nurse.
Once our laboratories receive your sample, foetal DNA is extracted, isolated, and analysed for the presence of Y male chromosomes. Any detection of this chromosome will reveal that you are having a boy. An absence of the Y chromosome reveals that you are having a girl.
Refund Policy
If it eventuates that a test has provided incorrect gender results, a full refund will be given. A refund will only be given after the birth of the child and upon presentation of a birth certificate.